Data Input

Load concentration-time data via file upload, manual entry, or Smart Parse.

File Upload / Manual Entry

Drop CSV/TSV file or click to browse
.csv, .txt, .tsv

Smart Parse

Instant

Paste anything — CSV, Excel table, JSON, or even a text description of your data. The AI will extract time-concentration pairs automatically.

Data Preview

No data loaded. Use one of the input methods above.

Analysis Configuration

Configure NCA parameters. Linear-up Log-down trapezoidal method with Best Fit λz selection.

Dosing Information

Required for CL, Vd, Vss calculations

Calculation Method

Linear-up Log-down Trapezoidal Rule
Ascending: linear trapezoid. Descending (both C > 0): log-linear trapezoid. C=0: linear fallback.
Best Fit λz Selection
Automated selection of terminal phase regression points using maximum adjusted R² criterion. Minimum 3 points, post-Tmax, C > 0, negative slope required.

Computed Parameters:

Cmax Tmax AUC(0-t) AUC(0-∞) AUMC(0-t) AUMC(0-∞) λz MRT CL/F Vz/F Vss/F

NCA Results

Complete pharmacokinetic parameter estimates.

Primary PK Parameters

Run analysis to see results.

Terminal Phase Regression (λz)

Run analysis to see terminal phase details.

Interval Data (AUC/AUMC Buildup)

Run analysis to see interval data.

PK Profile Visualization

Concentration-Time Profile

Click data points to manually select terminal phase points for λz regression.

Terminal Phase Residuals